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. 2014 Aug 13;9(8):e103091. doi: 10.1371/journal.pone.0103091

Table 4. Tuberculosis detection by indirect smear microscopy vs RPA IS6110.

Culture positive Culture negative
Indirect smear microscopy positive 34 5
Indirect smear microscopy negative 14 37
RPA IS6110 positive 42 2
RPA IS6110 negative 6 40

Testing pulmonary specimens (n = 90) by indirect smear microscopy and RPA IS6110 to detect tuberculosis, with comparison to liquid culture based test data. RPA IS6110 was more sensitive than indirect smear microscopy (87.5% (95% CI: 81.7, 93.2) vs 70.8% (95% CI: 62.91, 78.75)) and also more specific (95.4 (95% CI: 92.3, 98.1) vs 88% (95% CI: 83.6, 92.4)).