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. Author manuscript; available in PMC: 2015 Jan 3.
Published in final edited form as: Nature. 2014 May 28;511(7507):90–93. doi: 10.1038/nature13283

Figure 1.

Figure 1

Ribavirin resistance in some ribavirin monotherapy clinical trial patients. BM biopsies for responding (patient 8 achieved a PR; patient 11 a CR is shown in Figure 1A) and non-responding patients (patient 9 was a PD and patient 13, SD). Note abundance of blasts before treatment and at the end of treatment (EOT) and reduction in blasts and restoration of hematopoiesis during response. For Wright-Giemsa stained samples magnification was 50× with oil (patients 8 and 13), and for Lysozyme staining 20X (Patient 9).