Table 2. Gene counts belonging to immunity-related gene families.
| Gene family | Gene numbers | ||||
| Drosophila melanogaster a | Anopheles gambiae a | Apis mellifera a | Bombyx mori a | Musca domestica b | |
| Recognition | |||||
| PGRP | 13 | 7 | 4 | 12 | 16 |
| βGRP | 3 | 7 | 2 | 4 | 3 |
| fibrinogen-related protein | 14 | 61 | 2 | 3 | 19 |
| scavenger receptor | 21 | 21 | 13 | 18 | 13 |
| C-type lectin | 34 | 25 | 10 | 21 | 16 |
| hemocytin | 1 | 0 | 1 | 1 | 1 |
| galectin | 6 | 8 | 2 | 4 | 7 |
| TEP | 6 | 15 | 3 | 3 | 36 |
| nimrod | 10 | 4 | 4 | 4 | 8 |
| draper | 1 | 1 | 1 | 1 | 2 |
| eater | 1 | 1 | 0 | 0 | 0 |
| dscam | 1 | 1 | 1 | 1 | 1 |
| Modulation | |||||
| clip serine protease | 37 | 41 | 18 | 15 | 6 |
| serpin | 30 | 17 | 5 | 26 | 40 |
| Toll pathway | |||||
| spätzle | 6 | 6 | 2 | 3 | 1 |
| toll | 9 | 10 | 5 | 14 | 14 |
| MyD88 | 1 | 1 | 1 | 1 | 1 |
| tollip | 1 | 2 | 1 | 2 | 1 |
| tube | 1 | 1 | 1 | 1 | 1 |
| pellino | 1 | 1 | 1 | 1 | 1 |
| pelle | 1 | 1 | 1 | 1 | 1 |
| TRAF2 | 1 | 1 | 1 | 1 | 0 |
| ECSIT | 1 | 1 | 1 | 1 | 2 |
| cactus | 1 | 1 | 3 | 1 | 2 |
| Dif/Dorsal | 2 | 1 | 2 | 1 | 2 |
| IMD pathway | |||||
| IMD | 1 | 1 | 1 | 1 | 1 |
| DREDD | 1 | 1 | 1 | 1 | 1 |
| TAK1 | 1 | 1 | 1 | 1 | 1 |
| FADD | 1 | 1 | 1 | 1 | 1 |
| TAB2 | 1 | 1 | 1 | 1 | 2 |
| IAP2 | 1 | 1 | 1 | 1 | 1 |
| IKK | 2 | 2 | 2 | 2 | 1 |
| UBC13 | 1 | 1 | 1 | 1 | 0 |
| relish | 1 | 1 | 2 | 1 | 1 |
| JNK pathway | |||||
| HEM | 1 | 1 | 1 | 1 | 1 |
| JNK | 1 | 1 | 1 | 1 | 3 |
| FOS | 1 | 1 | 1 | 1 | 1 |
| JUN | 1 | 1 | 1 | 1 | 1 |
| JAK/STAT pathway | |||||
| UPD3 | 1 | 0 | 0 | 0 | 0 |
| PIAS | 1 | 1 | 1 | 1 | 1 |
| SOCS | 1 | 1 | 1 | 1 | 1 |
| domeless | 1 | 1 | 1 | 1 | 4 |
| hopscotch | 1 | 1 | 1 | 0 | 2 |
| STAT | 1 | 2 | 1 | 1 | 1 |
| Antimicrobial peptide | |||||
| ceropin | 4 | 4 | 0 | 13 | 3 |
| attacin | 4 | 1 | 0 | 2 | 9 |
| diptericin | 2 | 0 | 0 | 0 | 3 |
| defensin | 1 | 4 | 2 | 1 | 1 |
| gloverin | 0 | 0 | 0 | 4 | 0 |
| moricin | 0 | 0 | 0 | 9 | 0 |
| lebocin | 0 | 0 | 0 | 1 | 0 |
| domesticin * | 1 | 0 | 0 | 0 | 1 |
| muscin * | 0 | 0 | 0 | 0 | 1 |
| Melanization | |||||
| PPO | 3 | 9 | 1 | 2 | 7 |
| DDC | 1 | 7 | 1 | 1 | 2 |
| DCE | 2 | 0 | 18 | 16 | 4 |
| TH | 1 | 1 | 1 | 1 | 2 |
| punch | 1 | 0 | 1 | 0 | 1 |
| Other effectors | |||||
| NOS | 1 | 1 | 1 | 2 | 1 |
| POI | 2 | 1 | 0 | 1 | 0 |
| lysozyme | 11 | 8 | 2 | 4 | 13 |
| Other immune molecules | |||||
| caspase | 6 | 11 | 4 | 4 | 5 |
| dicer2 | 1 | 1 | 1 | 0 | 6 |
| argonaute2 | 1 | 1 | 1 | 1 | 2 |
| Total | 265 | 304 | 138 | 220 | 279 |