Figure 1. Domain architecture of A. aegypti Protein Tyrosine Phosphatases.

The ten Protein Tyrosine Phosphatase sequences from A. aegypti were analyzed for the presence biologically active domains. The domains were identified using a conserved sequence search as mentioned in the methods. Domain architecture was mapped onto the sequence using the DOG 1.0 protein-structure illustrator (DOG 1.0: illustrator of protein domain structures). Nomenclature used is as follows: PTP - Protein Tyrosine Phosphatase domain, PTP (br) - Absent Protein Tyrosine Phosphatase domain, SEC14 - Phosphatidylinositol transfer protein domain, FERM - F for 4.1 protein, E for ezrin, R for radixin and M for moesin, cytoskeletal association domain (includes the FA: FERM-associated domain) PDZ - also called DHR or GLGF, adaptor domain.