Figure 3.

¹¹¹In-DOTA-51 Cell Binding Competition. ¹¹¹In-DOTA-51 was diluted to 1 × 10⁶ CPM/mL in RPMI and 1% BSA and 100 µL was added to 1 million BT-474 cells suspended in 100 µL of the same buffer. Unlabeled DOTA-51 was serially diluted from 100 pM to 1 µM and added to labeled peptide and cells. Following a 1 h incubation at 37°C, cells were washed and bound radioactivity quantified. Square boxes reperesent the mean of 3 replicates and error bars represent standard deviation. CPM - Counts per minute.