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. 2014 Aug 19;9(8):e105112. doi: 10.1371/journal.pone.0105112

Table 2. Univariate analysis of predictors of lymph node metastasis.

Variable No metastasis Metastasis P
(n = 239) (n = 203)
Gender 0.335
Male 168 134
Female 71 69
Age (years) 0.526
≤50 64 49
>50 175 154
Tumor size (cm) 0.007
<6 220 170
≥6 19 33
Tumor location 0.662
Upper third 56 45
Middle third 39 26
Lower third 133 120
 Two or more thirds 11 12
Histological type 0.147
Well differentiated 10 3
Moderate differentiated 72 57
Poor differentiated 144 137
Undifferentiated 13 6
Depth of invasion in muscularis propria 0.022
Shallow layer 154 109
Deep layer 85 94
Vascular tumor emboli 0.000
Yes 29 76
No 210 127
Nervous invasion 0.097
Yes 30 37
No 209 166