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. 2014 Aug 19;9(8):e105008. doi: 10.1371/journal.pone.0105008

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© 2014 Lonati et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Indirect immunofluorescence analysis was used to assess the expression of IL-17A (green), in combination with CD3 (red, left panel) or Tryptase (red, right panel) and DAPI staining of nuclei (blue) in the dermis of a representative of 5 morphea biopsies. Original magnification 40X. B. Box-plots show the quantification of CD3+IL-17A+ and Tryptase+IL-17A+ cells expressed as percentage of total IL-17A+ cells in 4 HD, 4 SSc and 4 morphea skin section. The box represents values between 25^th and 75^th percentile with a line at the median (50^th percentile). The whiskers extend above and below the box to show the highest and the lowest values.