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. 2014 Aug 19;9(8):e104936. doi: 10.1371/journal.pone.0104936

Table 2. Subgroup analysis for accuracy of PLA2R-AB for MN detection.

Subgroup N Sensitivity Specificity DOR AUC
Race
Caucasian 10 0.80(0.62,0.91) 1.00(0.98,1.00) 1297 0.99(0.97–0.99)
Asian 5 0.72(0.67,0.77) 0.91(0.84,0.95) 26 0.91(0.88–0.93)
Sample size
<100 subjects 6 0.82(0.66,0.91) 0.97(0.78,1.00) 147 0.94(0.92–0.96)
> = 100 subjects 9 0.76(0.59,0.88) 0.99(0.97,1.00) 465 0.97(0.96–0.99)
Control
Patients 9 0.80(0.64,0.90) 0.98(0.89,1.00) 220 0.95(0.93–0.97)
Health 6 0.75(0.55,0.88) 1.00(0.98,1.00) 914 1.00(0.99–1.00)
Method
Western blotting 9 0.68(0.62,0.73) 0.97(0.93,0.99) 73 0.84(0.80–0.87)
Imunofluorescence 4 0.74(0.37,0.93) 0.99(0.78,1.00) 451 0.98(0.96–0.99)
ELISA 1 - - - -
Test interval
No 8 0.68(0.62,0.73) 0.95(0.86,0.98) 39 0.78(0.74–0.81)
After biopsy test 7 0.86(0.65,0.96) 1.00(0.98,1.00) 8710 1.00(0.99–1.00)
Funding by
Government foundation 9 0.70(0.56,0.81) 0.99(0.90,1.00) 177 0.89(0.86–0.92)
Corporation or no funding 6 0.88(0.76,0.95) 0.99(0.96,1.00) 843 0.99(0.98–1.00)