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. 2014 Aug 19;9(8):e105588. doi: 10.1371/journal.pone.0105588

Figure 5. Excision101 homozygous larvae have impaired UPR activation.

Figure 5

(A) Picture of 3-day old Excision101 homozygous larva and heterozygous Excision101/CyO-GFP sibling control. Excision101 homozygous larva arrest development during first instar stage. (B) Quantitative RT-PCR for BiP and Pdi mRNA levels in Excision101 homozygous or control heterozygous Excision101/CyO-GFP larvae treated with/without tunicamycin food. Induction of BiP and Pdi upon tunicamycin treatment is impaired in Excision101 homozygous larva. mRNA levels are indicated as a mean +/− standard deviation (a.u. - arbitrary units).