Table VI.
Meibum Lipid Composition
| Sample Pool | Resonance Area ratio Wax ester/CH2 |
Resonance Area ratio Cholesterylester/Wax |
Resonance Area ratio Glycerides/Wax |
|---|---|---|---|
| Normal (Mn)a | 0.026 ± 0.003, n = 32 | 0.28 ± 0.04, n = 26 | 0.37 ± 0.06, n = 40 |
| MGD enrolled | 0.021 ± 0.005, n = 10 | 0.21 ± 0.07, n = 12 | 0.45 ± 0.10, n = 12 |
| MGD (Md)a | 0.026 ± 0.003, n = 39 | 0.17 ± 0.02, n = 47 | 0.39 ± 0.04, n = 46 |
| MGD treated 2 to 4 weeks with azithromycin | 0.032 ± 0.011, n = 22 | 0.10 ± 0.028, n = 23 | 0.62 ± 0.07, n = 23 |
| MGD 2 to 4 weeks After treatment with azithromycin was stopped | 0.011 ± 0.016, n = 8 | 0.19 ± 0.08, n = 7 | 0.52 ± 0.09, n = 7 |
| MGD treated 4 to 8 weeks with Doxycycline | 0.053 ± 0.013, n = 11 | 0.05 ± 0.02, n = 10 | 0.45 ± 0.069, n = 11 |
| Normal vs MGD (p) | 0.97 | 0.0098* | 0.078 |
| Doxycycline treated vs MGD (p) | 0.004* | 0.012* | 0.53 |
Previously reported.11
Statistically significant, p < 0.05.