Table 3.
Incremental mean cost per quality adjusted life year (QALY) and per depression free day (DFD).
| Incremental Cost per QALY, $b (95% CI) | Incremental Cost per DFD, $b (95% CI) | |
|---|---|---|
| Actual All observations |
54,605 (44,593 to 64,617) | −4 (−391 to 384) |
| Actual, Excluding 1 high-cost outlier in CC groupc | −21,591 (−26,064 to −17,118) | −59 (−142 to 25) |
| Actual All observations Intervention cost doubled to $920 |
65,943 (55,234 to 76,653) | 44 (−320 to 409) |
| Estimateda, All observations | −9,889 (−11,940 to −7,838) | −48 (−64 to −31) |
| Estimateda, Excluding 1 high-cost outlier in CC groupc | −14,539 (−16,125 to −12,952) | −49 (−54 to −44) |
| Estimateda, All observations Intervention cost doubled to $920 |
3,743 (−163 to 7,649) | −13 (−26 to −1) |
a
QALYs and DFDs were estimated using a mixed model that included treatment, time point, age, gender, and race, and two- and three-way interaction terms between treatment, time point and gender and bootstrapped to calculate the ICER with 95% confidence intervals.
b
Costs were estimated using GLM model that included treatment group, age, gender, race and interaction term between treatment and gender. Assume $460 mean per capita cost for intervention unless otherwise noted.
c
The single extreme high-cost outlier in the CC group generated $258,801 in total 12-month costs.