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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Phys Med. 2014 Jun 26;30(6):619–634. doi: 10.1016/j.ejmp.2014.05.011

Fig. 5.

Fig. 5

In vivo cancer imaging using liposomal iodinated nanoparticles. Mice are inoculated with cancer cells 3 weeks prior to imaging, allowing xenograft tumors to grow. Imaging is performed immediately after the injection of liposomal iodinated nanoparticles (early phase) and 3 to 7 days later (delayed phase). The early-phase scan is used to measure tumor fractional blood volume, while the delayed-phase scan is used to measure tumor vessel permeability via the enhanced permeability and retention effect.