Figure 2.
Behavioral effects of each chemical injected into vehicle challenged skin (“control mice”). The mean number of bouts of scratching (A) and mean number of wipes (B) evoked by an injection of each chemical into the area of skin previously challenged with acetone alone. *P*P < 0.05, compared to normal saline injection, n = 8/group. Mann-Whitney Un = 8/group. Mann–Whitney U test was used to compare the differences between BAM- and NS-evoked scratching and HIST and NS-induced wiping. Abbreviations: NS, normal saline; HIST, histamine; BAM, BAM8-22; BK, bradykinin.