Table 3.

Two-way Sensitivity Analysis: Incremental Cost-Effectiveness Ratio of Imperfectly Informed Antigen-Matching Varying Sensitivity and Specificity of Assay. Each value in the table reflects the incremental cost to prevent an additional alloimmunization event using a strategy of imperfectly informed antigen-matching with an assay of a particular sensitivity and specificity. History-based antigen-matching was used as a reference strategy. The shaded cells (dark background, white text) represent values less than $50,000 per alloimmunization event averted.

		Specificity (%)
		80	82	84	86	88	90	92	94	96	98	100
Sensitivity (%)	50	178,235	161,992	145,749	129,507	113,264	97,021	80,778	64,535	48,293	32,050	15,807
	52	171,613	155,995	140,377	124,759	109,141	93,523	77,904	62,286	46,668	31,050	15,432
	54	165,481	150,442	135,402	120,363	105,323	90,283	75,244	60,204	45,164	30,125	15,085
	56	159,788	145,285	130,783	116,280	101,778	87,275	72,773	58,270	43,768	29,265	14,763
	58	154,487	140,485	126,482	112,480	98,477	84,475	70,472	56,470	42,468	28,465	14,463
	60	149,539	136,004	122,468	108,932	95,397	81,861	68,325	54,790	41,254	27,718	14,183
	62	144,911	131,812	118,713	105,614	92,515	79,416	66,317	53,218	40,119	27,020	13,921
	64	140,572	127,882	115,193	102,503	89,813	77,124	64,434	51,744	39,055	26,365	13,675
	66	136,496	124,191	111,886	99,581	87,275	74,970	62,665	50,360	38,055	25,750	13,444
	68	132,660	120,716	108,773	96,830	84,887	72,943	61,000	49,057	37,114	25,171	13,227
	70	129,043	117,441	105,839	94,237	82,635	71,033	59,431	47,829	36,227	24,625	13,023
	72	125,626	114,347	103,067	91,787	80,508	69,228	57,948	46,668	35,389	24,109	12,829
	74	122,395	111,420	100,445	89,470	78,495	67,521	56,546	45,571	34,596	23,621	12,646
	76	119,334	108,647	97,961	87,275	76,589	65,903	55,217	44,531	33,845	23,159	12,473
	78	116,429	106,017	95,605	85,193	74,781	64,369	53,957	43,545	33,133	22,721	12,309
	80	113,670	103,518	93,366	83,215	73,063	62,911	52,759	42,608	32,456	22,304	12,152
	82	111,045	101,141	91,237	81,333	71,429	61,525	51,620	41,716	31,812	21,908	12,004
	84	108,546	98,877	89,209	79,541	69,872	60,204	50,536	40,867	31,199	21,531	11,862
	86	106,162	96,719	87,275	77,832	68,388	58,945	49,501	40,058	30,614	21,171	11,727
	88	103,887	94,658	85,430	76,201	66,972	57,743	48,514	39,285	30,056	20,828	11,599
	90	101,713	92,690	83,666	74,642	65,618	56,595	47,571	38,547	29,523	20,499	11,476
	92	99,634	90,806	81,979	73,151	64,324	55,496	46,668	37,841	29,013	20,186	11,358
	94	97,643	89,003	80,364	71,724	63,084	54,444	45,804	37,165	28,525	19,885	11,245
	96	95,735	87,275	78,816	70,356	61,896	53,436	44,976	36,517	28,057	19,597	11,137
	98	93,905	85,618	77,331	69,044	60,757	52,469	44,182	35,895	27,608	19,321	11,034
	100	92,148	84,027	75,905	67,784	59,663	51,541	43,420	35,298	27 177	19,056	10,934