Skip to main content
. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Mech Dev. 2014 Feb 19;0:177–188. doi: 10.1016/j.mod.2014.02.003

Figure 4. 4xGTIIC:d2GFP expression is decreased in response to Yap knockdown and enhanced with Yap or Taz overexpression.

Figure 4

(A′,C′) d2GFP expression levels are decreased in yap/p53 MO injected embryos (C′) compared to the p53 control embryos (A′) at 2 dpf. (B′,D′) yap/p53 MO embryos have a smaller eye and decreased RPE expression (D′) compared to p53 MO control embryos. (E–E″) Overexpression of mCherry does not cause enhanced or ectopic d2GFP expression. (F–F″) Overexpression of Yap, (G–G″) Yap constitutive active (CA) transgene (yapS87A) or (H–H″) Taz results in enhanced and ectopic d2GFP expression in retinal progenitor cells (embryos are 30 hpf). Scale bar=50 μm in B.