Skip to main content
. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Mech Dev. 2014 Feb 19;0:177–188. doi: 10.1016/j.mod.2014.02.003

Figure 7. Vgll4b represses nuclear Yap/Taz-TEAD activity.

Figure 7

(A–B″) 4xGTIIC:d2GFP positive RPE cells expressing (A′) mCherry or (B′) Vgll4b. Arrows depict the mCherry and Vgll4b positive cells. (C) Quantification of d2GFP pixel intensity in mCherry + (n=19), mCherry – (n=38), dsRed/Vgll4b + (n=28), and dsRed/Vgll4b – (n=58) cell clones. More than 12 embryos were used for each condition. Error bars represent S.E.M. p=unpaired t-test with equal S.D. (D) Diagram of the relationship between Yap-Tead and Vgll4b-Tead in RPE cells expressing endogenous or overexpressed levels of Vgll4b.