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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Bioorg Med Chem. 2014 Jun 16;22(15):3971–3981. doi: 10.1016/j.bmc.2014.06.004

Figure 3.

Figure 3

Time-dependent inactivation of BoNT/A LC by BQ compounds

Inhibitors were preincubated with BoNT/A LC for various time periods and diluted 50 fold into SNAPtide substrate. Remaining activity was determined for each time point as a ratio of initial velocities.