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Tetrodotoxin (10 μmol/L) blocked oxytocin-induced colonic response in intragastric cold water stressed rats. A: Representative traces of the effect of tetrodotoxin (TTX) on oxytocin (OT)-induced colonic response in cold group. The drug was administered at the points marked by the arrows. B: Results of colonic smooth muscle strips contraction in cold group rats. aP < 0.05 vs data of TTX treatment (n = 6).
