Table 1.
Measures of Intestinal Morphology and Morphometry in Control Versus DIO Mice
| Measure | Control | DIO | P Value |
|---|---|---|---|
| Mean (sem) | Mean (sem) | ||
| Small intestine length (cm) | 46.7 (1.0) | 43.6 (1.3) | .02a |
| Small intestine weight (g) | 1.9 (0.09) | 1.8 (0.09) | .35 |
| Small intestine weight/length (g/cm) | 0.04 (0.002) | 0.04 (0.002) | .73 |
| Jejunal crypt depth (μm) | 70.1 (2.5) | 66.1 (0.8) | .14 |
| Jejunal villus height (μm) | 282.1 (8.0) | 333.8 (18.8) | .02a |
| Jejunal crypt density (#/mm submucosal circumference) | 18.4 (0.6) | 20.6 (0.7) | .04a |
| Jejunal crypt fission (% of total cross section) | 0.92 (0.1) | 1.15 (0.2) | .31 |
a
, Significant P < .05