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. 2014 Jun 23;155(9):3329–3338. doi: 10.1210/en.2013-2004

Figure 2.

Figure 2.

Impaired glucose tolerance in mice with pancreatic PTP1B deletion fed an HFD. Body weights of female (A) and male (B) control (Con) and panc-PTP1B KO mice fed regular chow (full lines) and an HFD (dotted lines). GTTs in female (C and D) and male (E and F) control and panc-PTP1B KO mice fed regular chow and HFD at 8 (C and E) and 24 (D and F) weeks of age. ITTs in female (G) and male (H) control and panc-PTP1B KO mice at 24 weeks of age. Data are presented as mean ± SEM; n = 6–9. *, P ≤ .05; **, P ≤ .01 control vs panc-PTP1B KO mice.