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. 2014 Aug 20;5:438. doi: 10.3389/fmicb.2014.00438

FIGURE 1.

FIGURE 1

Evasion of the inflammasome by virulent Francisella in bone marrow macrophages (BMM). BMM were infected with Fn MOI 250 and SchuS4 MOI 150. MOI were selected to match uptake of Fn and SchuS4. (A) Intracellular bacteria were enumerated at the indicated times after infection. (B) Western blots of cell lysates were probed for caspase-1 p10 and actin. (C) Culture supernatants were assessed for IL-1β by ELISA. Error bars represent SD. ns, not significant, BLD, below level of detection, *p < 0.05 compared to all other groups. Data are representative of two independent experiments.