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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Pflugers Arch. 2013 Jul 3;465(12):1775–1784. doi: 10.1007/s00424-013-1312-2

Figure 2. Ca2+ transients during ECC in zebrafish and rabbit ventricular myocytes.

Figure 2

Confocal line-scan images of Fluo-4 fluorescence and corresponding F/F0 profiles recorded in rabbit (A) and zebrafish (B) ventricular myocytes. The F/F0 profiles were obtained by averaging the fluorescence throughout the entire image. The myocytes were electrically stimulated at constant rate (0.75 Hz; marked by black arrowheads). Contributions of LTCC and RyR to the AP-induced Ca2+ transients are indicated by the brackets. C, caffeine-induced and the AP-induced Ca2+ transients recorded in zebrafish ventricular myocytes in control conditions and after inhibition of SERCA with thapsigargin (TG; 10 μM).