(c).

Source	Year	Transplants			Recipients			Number of cells
		Species	Strain	Cell type	Species	Strain	Location
Coyne et al. [42]	2006	Rat	Sprague-	Bone marrow MSCs from eGFP rats.	Rat	Sprague-Dawley	Striatum or hippocampus	50,000
			Dawley
		Sprague-Dawley rats are outbred instead of inbred so these are allogeneic grafts and not syngeneic (225 g females).
		Results
		Few GFP-positive MSCs were seen at either location at 7 days and almost none at 14 days after transplanting. MSCs elicited an inflammatory response. Activated macrophages and microglia were seen in the grafts.
Tambuyzer et al. [43]	2009	Mice	C57BL/6	Marrow stromal cells	Mice	FVB	Intracerebral right pelvic limb muscle	200,000
		Results
		Stromal cells are lost over 3-4 weeks. Activation of microglia cells (CD11b). Muscle grafts were rejected by T cells, but not cerebral grafts.
Chen et al. [44]	2011	Mice	C57BL/6	Neural progenitor cells that express eGFP from CAG promoter	Mice	C57BL/6	Hippocampus	100,000
						Balb/c
		Results
		Fewer GFP-positive cells in allogeneic grafts as compared to syngeneic. More activated microglia in allografts than syngeneic one. Neurogenesis is inhibited in allografts. This effect is reversed with NSAIDs.
Spears [47]	2011	Mice	129svj	Neuralized ESCs	Mice	129svj	Left striatum	1,000,000
				expressing eGFP.		CD-1
		Results
		Allografts were rejected quickly (5–7 days) by cytotoxic T cells. Little activated microglia were detected. Syngeneic grafts increase in size.