Table 3. CSF Biomarker Concentrations in Relation to Clinical Variables (Separate Linear Regressions with Age and Gender as Covariates).

	NF-La		MBP		S100B		H-FABP
	β	P	β	P	β	P	β	P
Diagnosis
Type I (refb)	0.000	NA	0.000	NA	0.000	NA	0.000	NA
Type II	−0.025	0.706	0.141	0.052	0.046	0.595	0.010	0.908
Others	−0.005	0.946	0.006	0.930	−0.079	0.360	−0.133	0.110
Psychosisc	0.085	0.343	−0.106	0.239	0.022	0.804	0.114	0.205
GAF-Fc	−0.083	0.358	−0.012	0.897	−0.052	0.566	0.111	0.216
GAF-Sc	−0.162	0.070	−0.044	0.624	−0.069	0.445	0.034	0.706
CGI scored	0.046	0.609	−0.087	0.336	0.056	0.532	−0.073	0.417
Years of sicknesse	0.066	0.473	0.072	0.432	0.054	0.553	0.149	0.102
No. of episodesc	−0.037	0.684	0.129	0.149	0.053	0.557	0.034	0.705

Abbreviations: NA, not applicable; NF-L, neurofilament light chain; MBP, myelin basic protein; S100B, calcium-binding protein S100B; h-FABP, heart-type fatty acid binding protein; CGI, Clinical Global Impression; GAF, Global Assessment of Function; NA, ........ .

^aLog transformed before statistical analysis.

^bBipolar type I as reference group.

^cData from 128 patients.

^dData from 127 patients.

^eData from 127 patients.