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. 2014 May 14;39(10):2387–2396. doi: 10.1038/npp.2014.86

Figure 5.

Figure 5

FosB/ΔFosB stimulation by appetitive odor-cue presentation in CB1 knockout (KO) and wild-type (WT) mice. The conditioned odor cue was found to significantly enhance FosB/ΔFosB expression in trained WT animals in the nucleus accumbens (NAC) (a) and dorsal striatum (dStr) (b) compared to sham-trained controls. No such increased expression could be observed for CB1 KO mice, neither in the NAC (c) nor the dStr (d). Data are expressed as means±SEM (p<0.05 is indicated by asterisks) (WT: trained and sham-trained: n=5; CB1 KO: trained n=4, sham-trained n=5).