Table 2.
The number of monocytes* in patients with and without infection
| Infection by day 15: | All patients
|
Patients with infection at 72 h eliminated (n = 7)
|
||||||
|---|---|---|---|---|---|---|---|---|
| Yes n = 26 | No n = 77 | Uncontrolled
|
Controlled for NIHSS
|
Yes n = 19 | No n = 77 | Uncontrolled
|
Controlled for NIHSS
|
|
| p | p | p | p | |||||
| Monocytes* (thou/microL) | 0.88 (0.58, 1.13) | 0.65 (0.46, 0.83) | 0.012 | NS | 1.04 (0.65, 1.20) | 0.65 (0.46, 0.83) | <0.001 | 0.063 |
| Predictive value | Uncontrolled
|
Controlled for NIHSS
|
Uncontrolled
|
Controlled for NIHSS
|
||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| Monocytes* (per thou/microL) | 10.14 (2.09–49.26) | 0.004 | 2.12 (0.30–15.16) | NS | 34.35 (4.86–242.74) | <0.001 | 8.81 (0.68–98.12) | p = 0.097 |
The number is higher among patients destined for infection in the first 15 days after stroke onset, and the difference is even more marked after eliminating patients with infection in the first 3 days after stroke onset. The difference in monocytes numbers is attenuated by controlling for stroke severity. Similarly, the odds for infection rises dramatically with every 1000 monocytes per microliter of blood and is most notable in those patients who are infection free at the time the blood was drawn.
Data are presented as median (interquartile range) and statistics are by Mann–Whitney U test.
Highest value by 72 h after stroke onset. thou/microL, thousand per microliter; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; CI, confidence interval; NS, not significant (p > 0.200).