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. Author manuscript; available in PMC: 2014 Aug 20.
Published in final edited form as: J Neurochem. 2012 Nov;123(0 2):148–155. doi: 10.1111/j.1471-4159.2012.07953.x

Table 2.

The number of monocytes* in patients with and without infection

Infection by day 15: All patients
Patients with infection at 72 h eliminated (n = 7)
Yes n = 26 No n = 77 Uncontrolled
Controlled for NIHSS
Yes n = 19 No n = 77 Uncontrolled
Controlled for NIHSS
p p p p
Monocytes* (thou/microL) 0.88 (0.58, 1.13) 0.65 (0.46, 0.83) 0.012 NS 1.04 (0.65, 1.20) 0.65 (0.46, 0.83) <0.001 0.063
Predictive value Uncontrolled
Controlled for NIHSS
Uncontrolled
Controlled for NIHSS
OR (95% CI) p OR (95% CI) p OR (95% CI) p OR (95% CI) p
Monocytes* (per thou/microL) 10.14 (2.09–49.26) 0.004 2.12 (0.30–15.16) NS 34.35 (4.86–242.74) <0.001 8.81 (0.68–98.12) p = 0.097

The number is higher among patients destined for infection in the first 15 days after stroke onset, and the difference is even more marked after eliminating patients with infection in the first 3 days after stroke onset. The difference in monocytes numbers is attenuated by controlling for stroke severity. Similarly, the odds for infection rises dramatically with every 1000 monocytes per microliter of blood and is most notable in those patients who are infection free at the time the blood was drawn.

Data are presented as median (interquartile range) and statistics are by Mann–Whitney U test.

*

Highest value by 72 h after stroke onset. thou/microL, thousand per microliter; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; CI, confidence interval; NS, not significant (p > 0.200).