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. Author manuscript; available in PMC: 2014 Nov 22.
Published in final edited form as: Nature. 2014 Apr 9;509(7501):492–496. doi: 10.1038/nature13180

Extended Data Figure 7. Tumorigenic growth of NRAS mutation-positive human melanoma cancer cell lines upon knockdown of CTR1.

Extended Data Figure 7

a, RT-PCR detection of the amount of endogenous CTR1 and GAPDH mRNA and b, mean tumor volume (cm3) ± s.e.m. versus time (days) in mice (n=3) injected with the NRAS mutation-positive (NRASQ61L) human melanoma cell lines DM598 and DM792 stably infected with a retrovirus expressing either a scramble (SCRAM) shRNA (black circle) or CTR1 shRNA (red square). ****P<0.0001.