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. Author manuscript; available in PMC: 2014 Nov 22.
Published in final edited form as: Nature. 2014 Apr 9;509(7501):492–496. doi: 10.1038/nature13180

Extended Data Figure 10. Graphical representation of Cu regulation of BRAFV600E-mediated signaling and tumorigenesis.

Extended Data Figure 10

Inactivation of the signaling pathway is denoted in grey and dashed lines, gain of function mutations are denoted in green and loss of function mutations are denoted in red.