Table 1.
Phenotypic markers for Cell Discrimination. Lineage negative = Lin-; Lineage markers include CD3, CD14, CD20, CD66, and CD56.
Cell Type | Phenotypic Markers |
---|---|
Hematopoietic Stem Cell (HSC) | Lin-CD34+CD38- |
Hematopoietic Progenitor Cell (HPC) | Lin-CD34+CD38+ |
Common Myeloid Progenitor (CMP) | Lin-CD34+CD38+CD123loCD45RA- |
Common Lymphoid Progenitor (CLP) | Lin-CD34+CD38+CD10+ |
Granulocyte/Monocyte Progenitor (GMP) | Lin-CD34+CD38+CD123+CD45RA- |
Granulocyte (PMN) | HLA-DR-CD66+ |
Macrophage (Mac) | CD13+/CD33+HLA-DR+CD14+CD16+ |
Type 1 Myeloid Dendritic Cell (mDC1) | CD13+/CD33+HLA-DR+CD16+CD14+/-CD11c+CD1c+ |
Osteoclast Progenitor (OCP) | CD13+/CD33+HLA-DR+/-CD16-CD14+/-CD11c+/-CD1c-/RANK+ |
Differentiating Osteoclast (diff OC) | CD13+/CD33+HLA-DR-CD66-CD16-CD14-CD11c-CD1c-/RANK+αVβ3+ |
B Cell | CD3-CD20+ |
CD4 T Cell | CD3+CD8-CD4+ |
CD8 T Cell | CD3+CD8+CD4- |