Table 4. Effect of albumin on CME potency of the Dyngo compounds.

Compound	1 h	10% FBS	5% FBS	1% FBS	1% BSA	0.1% BSA
Dynasore	22.2 ± 6.0	532	650	57.8	235	277
4a	6.3 ± 3.6	115 ± 7.5	102	23.7 ± 3.2	83 ± 12	44
6a	3.3 ± 0.6	108 ± 15	78 ± 7	16.5	281	46

Table shows IC₅₀ values for inhibition of CME in U2OS cells after incubation of cells for 1 h in the presence or absence of FBS or BSA and the indicated compound. Data are mean (μM) and SEM or range of two to four independent experiments (1 h, n = 3; 1% FBS, n = 2; 10% FBS, n = 4).