Table 1.

Inhibitory effect of indolylchalcone (5a–g) and pyrido[2,3-d]pyrimidine derivatives (7a–k) on hCA I and hCA II.

Compound	hCA I IC50 (μM)	hCA II IC50 (μM)
5a	8.34	8.88
5b	7.42	10.35
5c	13.07	12.28
5d	8.20	8.26
5e	12.84	9.15
5f	10.87	9.31
5g	8.38	7.22
7a	16.29	19.42
7b	11.56	12.06
7c	21.09	31.10
7d	12.14	13.66
7e	6.79	8.06
7f	26.21	25.40
7g	7.61	7.57
7h	12.36	24.67
7i	8.72	8.14
7j	10.19	9.56
7k	22.30	26.68