Table 2.
Studies of imaging modalities to assess fracture status in patients with CKD that report test diagnostic characteristics
| Study | Kidney function | Imaging modality | Site imaged | Fracture site | Area under the receiver operator curve | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|
| Jamal et al. (2006)66 | ESRD | DXA pQCT | Total hip | Any site | 56 | 26 | 78 |
| Radius (cortical density) | Any site | 89 | NA | NA | |||
| Radius (trabecular density) | Any site | 52 | NA | NA | |||
| Jamal et al. (2002)65 | ESRD | DXA | Femoral neck | Any site | 47.3 | 26 | 78 |
| Ultrasound | Calcaneous | Any site | 56.2 | 29 | 78 | ||
| Fontaine et al. (2000)85 | ESRD | DXA | Femoral neck | Any site | 75.5 | NA | NA |
| Radius (mid) | Any site | 83.7 | NA | NA | |||
| Radius (one-third) | Any site | 78.0 | NA | NA | |||
| Lumbar Spine | Any site | 72.8 | NA | NA | |||
| Yamaguchi et al. (1996)52 | ESRD | DXA | Lumbar spine | Vertebral | 72.9 | 70 | 70 |
| Non-spine | 69.3 | 63 | 63 | ||||
| Radius (one-third) | Vertebral | 75.2 | 69 | 69 | |||
| Radius (ultradistal) | Non-spine | 86.9 | 82 | 82 | |||
| Atsumi et al. (1999)21 | ESRD | DXA | Total body | Vertebral | 55 | NA | NA |
| Lumbar spine | Vertebral | 60 | NA | NA |
CKD, chronic kidney disease; DXA, dual-energy X-ray absorptiometry; ESRD, end-stage renal disease; NA, not applicable; pQCT, peripheral quantitative computed tomography.