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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Aquat Toxicol. 2014 Jun 20;155:151–159. doi: 10.1016/j.aquatox.2014.06.006

Table 1.

Gene transcription data for gfap (glial fibrillary acidic protein; log2(fold-change), p value), a marker of astrocyte activation and neuroinflammation, as measured by microarray. Transcriptional changes are shown for animals exposed to domoic acid relative to the time-matched vehicle controls. Note that all array probes for this gene are non-significant, highlighting the absence of gross neuroinflammation and corroborating the histopathological assessment presented in Figure 1.

NCBI GenBank ID Probe ID gfap Log2(fold-change) (p value)
2 weeks 6 weeks 12 weeks 18 weeks 24 weeks 36 weeks
NM_131373 A_15_P107505 0.33 (0.19) 0.02 (0.93) 0.14 (0.56) 0.45 (0.07) 0.13 (0.59) −0.14 (0.57)
NM_131373 A_15_P131871 0.02 (0.77) −0.03 (0.65) 0.03 (0.64) 0.05 (0.47) −0.03 (0.67) −0.07 (0.30)
AY397679 A_15_P551122 0.00 (0.90) 0.01 (0.78) −0.01 (0.71) −0.02 (0.30) 0.00 (0.88) −0.01 (0.62)
NM_131373 A_15_P658936 0.05 (0.57) −0.01 (0.91) 0.04 (0.59) 0.19 (0.02) 0.03 (0.73) −0.05 (0.55)