Table 2.

Effect of the CRHR1 SNP Genotype × Stress interaction on the likelihood of alcohol dependence diagnosis

CRHR1 SNP	Chromosomal Position *	CRHR1 Location	MAF	HWE p-value	Base variation	p-value
rs4792886	41232603	intron	0.096	0.837	G > A	0.498
rs110402	41235818	intron	0.461	0.087	C > T	0.019
rs242924	41241147	intron	0.461	0.139	C > A	0.019
rs242942	41247413	intron	0.110	0.730	G > A	0.408
rs3785877	41247968	intron	0.041	0.074	G > A	0.269
rs171440	41249267	intron	0.487	0.558	C > T	0.056
rs242939	41251360	intron	0.070	0.796	A > G	0.912
rs4566211	41251477	intron	0.218	0.496	G > A	0.150
rs242936	41254990	intron	0.104	0.769	C > T	0.623
rs17762954	41255567	intron	0.218	0.418	C > T	0.175
rs173365	41256855	intron	0.429	0.811	C > T	0.026
rs1396862	41258778	intron	0.218	0.496	C > T	0.150
rs17763086	41261262	intron	0.218	0.511	T > G	0.141
rs17763104	41261576	intron	0.119	0.534	G > A	0.908
rs16940665	41263677	coding	0.218	0.458	T > C	0.143
rs17689918	41265869	intron	0.218	0.537	G > A	0.147
rs17689966	41266236	intron	0.428	0.738	A > G	0.018
rs1876829	41267224	intron	0.222	0.608	A > G	0.095
rs16940686	41268811	3UTR	0.040	0.153	G > T	0.223

Note:

^*Genome Build 36.3.

Significant traumatic stress × CRHR1 SNP interactions are bolded.