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. 2014 Jul 28;53(32):5249–5260. doi: 10.1021/bi500669u

Figure 7.

Figure 7

Comparison of structures of various Big domains (invasin, 1CWV; intimin, 1F00; BC Big_3, 2KPN; SP Big_3, 2L7Y), highlighting folding patterns and secondary structures. A set of structures illustrates the relationship between the position of the C and C′ loop and the length of sheet 2. The Greek key structure of invasin, intimin, and LigB-12 is colored yellow. Note the lack of the Greek key structure due to the absence of D and E β-strands in Big_3 domains. The length of the D–E loop is highly variable among Lig domains. An alignment of sequences for the illustrated structures can be found in the Supporting Information (Figure S3).