Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jun 25;289(32):21888–21895. doi: 10.1074/jbc.M114.582866

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 1. — The miR-23a/27a/24 and miR-23b/27b/24 clusters correlate with breast cancer metastasis. A, upper panel, schematic representing the chromosomal locations of human miR-23ab/27ab/24. Lower panel, sequence alignment of the miR-23ab/27ab/24 clusters. Seed sequences are highlighted in red, and miRNA members with identical seed sequences are color-coded. B, box plots showing normalized expression levels of indicated miRNAs in human primary (Pri) tumor and metastasis (Met) samples (n = 10). p values were based on Student's t test. C–E, normalized qRT-PCR expression of miR-23ab, miR-27ab, and miR-24 in 4T1 (C), MCF10A (D), or MDA-MB-231 (E) cell line series, as shown by heat maps. Data represent average, U6-normalized expression.