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BDNF-induced GluA1 phosphorylation after inflammation requires PLC-PKC pathway activation. A–C, Western blot (top panels) and summarized data (bottom panel) of NRM GluA1 and pGluR1 Ser-831 in CFA-injected rats treated by NRM infusion of TrkB-IgG (A, 100 ng), the PLC inhibitor U73122 (B, 0.5 ng), or the PKC inhibitor GF109203X (C, 100 ng) (n = 6 rats/group). Data are mean ± S.E. *, p < 0.05.
