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. 2014 Jun 18;289(32):22358–22364. doi: 10.1074/jbc.M114.571950

FIGURE 6.

FIGURE 6.

Deficiency in SUMOylation reduces Sharp-1 suppression of adipogenesis. A, expression of PPARγ and aP2 in Sharp-1 and Sharp-1m-transfected 3T3-L1 cells was measured on day 2 after DMIR treatment. *, p < 0.01; Student's t test; differences between Sharp-1 versus control or Sharp-1 versus Sharp-1m. B, vector control, Sharp-1, or Sharp-1 mutant-transfected 3T3-L1 cells were stained with Oil Red O on day 6 after DMIR treatment. C, Senp1+/+ MEF cells and vector, Sharp-1, or Sharp-1 mutant-transfected Senp1−/− MEF cells were stained with Oil Red O on day 8 after DMIR treatment.