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The effects of suppression of PP2A B56β or PR110 on cytotoxicity induced by various metals. A, L02 cells were infected with vectors encoding shRNAs targeting B56β and PR110 to generate stable cell lines indicated. Immunoblotting assay was performed to detect the gene suppression. B, the cell viability was measured upon various metal treatments at different concentrations in L02 cells with PP2A B56β or PR110 suppression. Data are presented as the mean ± S.E. from three experiments.
