Effect of 8-day exercise intervention on (a) CREB and (b) pCREB in (i) Sprague Dawleys, (ii) SHHF lean and (iii) SHHF obese rats. Eight days of moderate exercise did not significantly change CREB or pCREB activity in the SD, SHHF lean or SHHF obese rats: Sprague Dawleys (sedentary: n = 8, exercise: n = 10), SHHF lean rats (sedentary: n = 8, exercise: n = 10) and SHHF obese rats (sedentary: n = 9, exercise: n = 9). Data are expressed as mean fold change from sedentary groups + SEM.
CREB: cyclic adenosine monophosphate response element binding protein; pCREB: phosphorylated CREB; SEM: standard error of mean.