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. 2014 Aug 20;9(8):e105120. doi: 10.1371/journal.pone.0105120

Figure 3. Small intestinal cytokine responses in NOD2 deficient mice following ileitis induction.

Figure 3

(A) Nitric oxide, (B) IFN-γ, (C) TNF-α, and (D) IL-10 levels were determined in ex vivo ileal biopsies derived from C57BL/6 wildtype (WT; black circles) and NOD2 deficient (NOD2-/-; white circles) seven days following ileitis induction (ILE) as described in methods. Naive mice served as negative controls (N). Numbers of analyzed mice (in parentheses), means (black bars) and levels of significance (P-values) as compared to the respective groups (determined by Mann-Whitney-U test) are indicated. Data shown are representative for three independent experiments.