Table 1. Statistics on vFam performance on metagenomic datasets.

Virus Dataset	Total Reads	Positive Reads (%)	TP	FP	Precision	FPR	TPR	TPR/FPR
Human klassevirus 1	533,453	483 (0.09%)	358	9,957	3.47%	1.87%	74.12%	39.7
Santeuil nodavirus	20,787	2,493 (11.99%)	542	201	72.95%	1.10%	21.74%	19.8
CAS virus	19,196,993	122,911 (0.64%)	5,369	14,952	26.42%	0.08%	4.37%	55.7

Results for viral detection of Human klassevirus 1, Santeuil nodavirus, and CAS virus. TP = True Positives, FP = False Positives, Precision = TP/(TP+FP), TPR = TP/Positive Reads, FPR = FP/(Total Reads–Positive Reads); TP and FP determined from maximal values in Figures 4B, 4D, and 4F.