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. 2014 Aug 20;9(8):e105004. doi: 10.1371/journal.pone.0105004

Figure 3. MAPK/FGF and Wnt pathway genes differentially expressed in the 25 dpa regenerating lizard tail.

Figure 3

(A, B) Based on RNA-Seq analysis described in Figure 2, the heatmaps show the 10 MAPK/FGF pathway genes (A), or 9 Wnt pathway genes (B) defined by KEGG, that were differentially expressed, i.e., displayed significant differences between any two segments in the regenerating tail as determined by Cuffdiff2 (p<0.05), along with previously identified Wnt inhibitors. A diagram summarizing the tail segment(s) with highest expression level for each MAPK/FGF (A) or Wnt (B) pathway gene is also shown. Differentially expressed genes are denoted with an asterisk.