Table 1. Selected Genes Ontology categories represented along the regenerating tail axis.

	Category	GO Term	Description	Count	P-value	Genes
Cluster I
	myogenesis	GO:0006936	muscle contraction	30	6.63E-29	mybpc2, tnnc2, tnnc1, myl3, mybpc1, mybpc3, myl1, pgam2, myot, des, myom2, myl6b, myom1, chrna1, scn5a, dtna, kcnma1, actc1, acta1, actn2, myh6, tnni2, trdn, tnnt3, tnnt1, ryr1, stbd1, chrne, casq2, chrng
		GO:0007517	muscle organ development	28	3.44E-22	mef2c, myod1, myl2, tnnc1, myl3, mybpc3, myl1, trim72, speg, myl6b, pax7, obsl1, mkx, mkl2, chrna1, actc1, acta1, mstn, mylpf, myh6, csrp3, flnb, murc, neb, xirp1, itga7, vgll2, tcf15
		GO:0007519	skeletal muscle tissue development	9	3.73E-07	myod1, acta1, myl3, myl6b, pax7, mylpf, vgll2, chrna1, csrp3
		GO:0042692	muscle cell differentiation	11	4.86E-07	myod1, actc1, acta1, xirp1, myl2, speg, lgals1, obsl1, myh6, mkl2, chrna1
		GO:0050881	musculoskeletal movement	6	1.14E-06	tnnt3, tnnt1, tnnc2, tnnc1, chrna1, tnni2
		GO:0030029	actin filament-based process	14	1.28E-06	actc1, tnxb, myl2, acta1, myl1, pdlim3, myh6, gas7, flnb, xirp1, xirp2, myl6b, limch1, obsl1
		GO:0007155	cell adhesion	21	3.41E-05	hapln1, tnxb, mybpc2, clstn2, egfl6, lpp, mybpc1, col22a1, mybpc3, col28a1, mgp, actn2, col2a1, actn3, ecm2, col9a1, itga7, acan, susd5, col11a2, thbs4
		GO:0001501	skeletal system development	12	4.79E-04	bmp3, col9a1, col9a2, tbx15, lect1, clec3a, pax7, acan, mgp, col2a1, col11a2, tcf15
		GO:0030198	extracellular matrix organization	7	7.29E-04	csgalnact1, tnxb, adamts20, acan, col2a1, col11a2, ecm2
		GO:0030705	cytoskeleton-dependent intracellular transport	4	0.0166	actc1, myl6b, myl1, myh6
		GO:0006873	cellular ion homeostasis	11	0.0055	kcnma1, jph2, xirp1, pygm, atp2a1, ryr1, chrna1, chrne, csrp3, sypl2, chrng
	chondrogenesis	GO:0051216	cartilage development	8	1.10E-05	bmp3, col9a1, lect1, pax7, acan, mgp, col2a1, col11a2
		GO:0002062	chondrocyte differentiation	4	7.90E-04	col9a1, acan, col2a1, col11a2
		GO:0001502	cartilage condensation	3	0.0162	acan, mgp, col2a1
	musculoskeletal activity	GO:0043462	regulation of ATPase activity	5	1.82E-05	tnnt3, myl3, tnnc1, mybpc3, myh6
		GO:0006029	proteoglycan metabolic process	4	0.0099	csgalnact1, lect1, acan, col2a1
	biological adhesion	GO:0022610	biological adhesion	21	3.48E-05	hapln1, tnxb, mybpc2, clstn2, egfl6, lpp, mybpc1, col22a1, mybpc3, col28a1, mgp, actn2, col2a1, actn3, ecm2, col9a1, itga7, acan, susd5, col11a2, thbs4
Cluster II
	wound response	GO:0009611	response to wounding	10	0.0040	pcsk1, scube1, pdgfra, pla2g7, entpd1, ptx3, mdk, igfbp4, f2r, spp1
		GO:0009725	response to hormone stimulus	8	0.0059	cga, pcsk1, krt19, tnfrsf11b, bsg, th, pdgfra, spp1
		GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	3	0.0067	wnt5a, wnt16, ror2
		GO:0016055	Wnt receptor signaling pathway	5	0.0079	dkk2, wnt5a, wnt16, ror2, wif1
		GO:0007166	cell surface receptor signaling pathway	20	0.0106	wnt5a, cga, edn3, fgfr4, il1r1, wnt16, gpr158, bsg, maml2, ptpn22, thy1, dkk2, ednra, or5v1, pdgfra, ror2, wif1, pdgfc, entpd1, f2r
		GO:0010033	response to organic substance	11	0.0098	ednra, cga, pcsk1, krt19, il1r1, tnfrsf11b, bsg, th, pdgfra, f2r, spp1
		GO:0006954	inflammatory response	6	0.0433	scube1, pla2g7, ptx3, igfbp4, f2r, spp1
	hormonal regulation	GO:0051050	positive regulation of transport	7	0.0020	ednra, edn3, pcsk1, rab8b, ptx3, f2r, thy1
		GO:0032844	regulation of homeostatic process	5	0.0046	ednra, tnfrsf11b, f2r, spp1, thy1
		GO:0006590	thyroid hormone generation	2	0.0350	cga, dio2
	embryonic morphogenesis	GO:0001501	skeletal system development	9	5.81E-04	wnt5a, tnfrsf11b, pdgfra, ror2, mepe, cbfb, igfbp4, spp1, twist1
		GO:0035295	tube development	7	0.0019	wnt5a, ednra, fgfr4, sall1, pdgfra, ptk7, twist1
		GO:0048598	embryonic morphogenesis	7	0.0096	wnt5a, sall4, th, ptk7, ror2, twist1, ptprq
	immune response	GO:0006030	chitin metabolic process	2	0.0407	chi3l1, chit1