Table 1. Baseline subject characteristics.
ADNI | ADNI Subset | AddNeuroMed | |||||||
CTL | MCI | AD | CTL | MCI | AD | CTL | MCI | AD | |
N | 191 | 226 | 147 | 18 | 89 | 4 | 110 | 119 | 119 |
Age | 75.8±5.0 | 74.7±6.9 | 75.0±7.4 | 77.7±5.4 | 74.7±7.5 | 77.2±6.6 | 72.9±6.5 | 74.3±5.7 | 75.5±6.0 |
Female/Male | 94/97 | 84/142 | 71/76 | 7/11 | 37/52 | 2/2 | 60/50 | 59/50 | 60/40 |
Education | 16.1±2.8 | 15.8±2.9 | 14.8±3.0 | 16.6±2.6 | 15.6±3.0 | 13±3.8 | 10.8±4.8 | 8.9±4.3 | 8.0±4.0 |
MMSE | 29.1±1.0 | 27.1±1.8 | 23.4±1.9 | 29.1±0.8 | 26.7±1.6 | 25.0±1.4 | 29.1±1.2 | 27.1±1.7 | 20.9±4.7 |
CDR-SOB | 0.03±0.1 | 1.56±0.9 | 4.26±1.6 | 0.03±0.1 | 1.66±0.9 | 4.00±0.9 | 0.06±0.2 | 1.38±0.9 | 6.50±3.2 |
ApoE 4+ (%) | 25.1 | 48.7 | 64.0 | 38.9 | 62.9 | 100 | 28.2 | 32.8 | 53.8 |
Data shown as mean ± standard deviation. Education is presented in years. ADNI subset refers to the group of reverters and later converters which were used for validation of the model but were not included in the training of the model. AD = Alzheimer’s disease, MCI = Mild Cognitive Impairment, CTL = healthy control, MMSE = Mini Mental State Examination. CDR-SOB – Clinical Dementia Rating – Sum Of Boxes.