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. 2014 Aug 20;9(8):e105196. doi: 10.1371/journal.pone.0105196

Figure 7. Protriptyline Does Not Affect Other Proteases.

Figure 7

Effect of protriptyline on A. Trypsin B. ADAM 17activity. Specific synthetic substrate BApNA and fluorogenic peptide was used for analyzing activity on trypsin and ADAM 17, respectively. Trypsin activity was unaffected, while ADMA 17 showed weak inhibition in presence of protriptyline.