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. 2014 Aug 20;9(8):e105263. doi: 10.1371/journal.pone.0105263

Table 1. Summary of most significant enriched GO Biological Process terms in reconstructed skins exposed to UVA1.

Number of GO terms Pvalue min Pvalue max
Up-regulated probe sets in fibroblasts
Response to stimulus 19 2.4e-12 2.7e-07
Cell death/Apoptosis 11 5.9e-12 2.5e-07
Signaling 12 3.9e-10 2.9e-07
Protein modification 3 1.3e-08 1.7e-07
Cell communication 2 9.8e-08 2.7e-07
Regulation of metabolic process/biological process 4 1.0e-07 1.8e-07
Down-regulated probe sets in fibroblasts
Response to virus 5 8.1e-12 3.2e-11
Response to cytokine/Innate immunity 4 9.8e-08 5.6e-07
Development/Morphogenesis 28 3.3e-09 1.3e-05
Cell migration/Motility 6 3.2e-08 2.9e-06
Signaling 2 7.6e-07 2.2e-06
Response to stimulus 5 7.8e-07 4.4e-06
Up-regulated probe sets in keratinocytes
Response to stimulus 21 2.3e-11 7.8e-06
Signaling 13 4.6e-09 4.2e-06
Cell communication 3 3.8e-08 1.1e-06
Cell death/Apoptosis 4 6.0e-07 6.7e-06
Glucose metabolism 3 3.2e-07 3.8e-06
Phosphate metabolism 2 1.9e-06 3.6e-06
Protein metabolism 2 3.4e-06 7.4e-06
Development 1 9.2e-07 9.2e-07
Oxidative stress response 1 5.2e-06 5.2e-06
Down-regulated probe sets in keratinocytes
Lipid metabolism 24 1.9e-06 0.0033
Response to virus 13 4.9e-06 0.0034
Metabolic process 6 0.00012 0.0014
Cell migration 2 0.0028 0.0028
Response to stress 2 0.0028 0.0033
Miscellanous 3 0.00017 0.0024

Summary of the list of the top 50 enriched GO terms related to Biological Process (BP) for the up-regulated probe sets and down-regulated probe sets in fibroblasts and keratinocytes of reconstructed skins exposed to UVA1. The detailed lists are given in Tables S2 and S3, for fibroblasts and keratinocytes, respectively.