Figure 2. Viable organisms in the brain and lungs of zyxin-deficient and wild-type mice following intranasal inoculation of H. influenzae in CBOs. Brain and lung H. influenzae concentrations in zyxin-deficient and wild-type mice infected with intranasal CBO; the mice died due to infection. These data correspond to the experiment shown in Figure 3. (A) H. influenzae log10 cfu/brain as a function of time post-infection. (B) H. influenzae log10 cfu/lung as a function of time post-infection. Data are plotted by day of death. Open circles, wild type; closed squares, zyxin-deficient mice