Table 3.
White matter changes between task-specific dystonia (TSD), non-task-specific dystonia (NTSD) and controls
| Brain region | F-score | x,y,z | ||
|---|---|---|---|---|
| Initial ANOVA | Left | Middle Frontal Gyrus | 15.65 | −25, 34, 2 |
| Right | Middle Frontal Gyrus | 15.04 | 34, 36, 1 | |
| Left | Primary Sensorimotor Cortex | 17.66 | −24, −31, 47 | |
| Right | Primary Sensorimotor Cortex | 15.82 | 23, −32, 48 | |
| Left | Occipital Cortex | 13.20 | −34, −73, 3 | |
| Right | Occipital Cortex | 11.39 | 34, −71, −7 | |
| Left | Corpus Callosum (Genu) | 23.51 | −8, 29, 1 | |
| Right | Corpus Callosum (Genu) | 22.02 | 4, 26, 1 | |
| Left | Corpus Callosum (Splenium) | 23.30 | −4, −33, 20 | |
| Right | Corpus Callosum (Splenium) | 25.22 | 1, −39, 13 | |
| Left | Thalamus | 17.24 | −12, −6, 13 | |
| Right | Thalamus | 16.97 | 15, −15, 17 | |
| Midbrain/Pons | 13.79 | −4, −21, −8 | ||
| Left | Cerebellum (lobules VI/VIIa) | 11.62 | −17, −57, −24 | |
| Right | Cerebellum (lobules VI/VIIa) | 11.26 | 14, −49, −25 | |
| Left | Operculum/Insula | 13.11 | −27, −1, 28 | |
| Left | Inferior Parietal Lobule/Supramarginal Gyrus | 12.97 | −42, −47, 31 | |
| Left | Middle Temporal Gyrus | 17.91 | −40, −44, −2 | |
| Left | Inferior Temporal Gyrus | 14.29 | −43, −7, −25 | |
| White matter changes in NTSD/TSD vs. controls | ||||
| Decreased Fractional Anisotropy | T-score | x,y,z | ||
| NTSD vs. Controls | Left | Middle/Inferior Frontal Gyri | −7.46 | −31, 43, −2 |
| Right | Middle/Inferior Frontal Gyri | −5.41 | 31, 42, −2 | |
| Left | Corpus Callosum (Genu/Body) | −7.95 | −16, 36, 0 | |
| Right | Corpus Callosum (Genu/Body) | −7.24 | 13, 25, 18 | |
| Left | Internal Capsule (Anterior limb/Genu) | −4.21 | −18, 16, 2 | |
| Right | Internal Capsule (Anterior limb/Genu) | −5.54 | 11, 5, −5 | |
| Right | Primary Sensorimotor Cortex | −3.99 | 48, 2, 28 | |
| Right | Inferior Temporal gyrus | −5.69 | 44, 1, −32 | |
| Increased Fractional Anisotropy | ||||
| Corpus Callosum (Splenium) | 4.82 | 0, −37, 17 | ||
| Left | Cingulate Gyrus | 7.38 | −9, −8, 33 | |
| Right | Cingulate Gyrus | 4.62 | 9, −9, 34 | |
| Left | Occipital cortex | 5.72 | −24, −80, 4 | |
| Right | Occipital cortex | 6.40 | 37, −47, 1 | |
| Midbrain/Pons | 3.99 | −9, −28, −26 | ||
| Left | Cerebellum (lobule VIIa) | 6.17 | −21, −68, −39 | |
| Right | Cerebellum (lobule VIIa) | 6.07 | 15, −74, −36 | |
| Right | Ventral Thalamus | 5.22 | 3, −13, 3 | |
| Decreased Fractional Anisotropy | ||||
| TSD vs. Controls | Left | Middle Frontal Gyrus | −4.45 | −27, 42, −3 |
| Right | Middle Frontal Gyrus | −3.04 | 33, 42, −2 | |
| Right | Internal capsule (Anterior limb/Genu) | −4.30 | 10, 5, 1 | |
| Left | Corpus Callosum (Genu) | −3.79 | −15, 37, 1 | |
| Increased Fractional Anisotropy | ||||
| Left | Cerebellum | 3.97 | −9, −51, −30 | |
| White Matter Changes in TSD vs. NTSD | ||||
| T-score | x,y,z | |||
| TSD > NTSD | Left | Middle/Inferior Frontal Gyrus | 5.15 | −15, 34, −6 |
| Right | Middle/Inferior Frontal Gyrus | 5.92 | 23, 37, −3 | |
| Left | Corpus Callosum (Genu) | 5.42 | −6, 28, 5 | |
| Right | Corpus Callosum (Genu) | 5.37 | 13, 31, 8 | |
| Left | Putamen | 3.24 | −22, −5, 15 | |
| Right | Putamen | 3.86 | 23, −6, 14 | |
| Right | Premotor Cortex | 4.17 | 45, 0, 28 | |
| Right | Internal Capsule (Anterior Limb/Genu) | 3.91 | 23, −4, 16 | |
| NTSD > TSD | Left | Middle Cingulate Cortex | 4.58 | −10, −31, 32 |
| Right | Middle Cingulate Cortex | 4.67 | 10, −28, 34 | |
| Left | Primary Sensorimotor cortex | 4.38 | −37, −14, 31 | |
| Left | Inferior Parietal Lobule | 4.27 | −35, −43, 32 | |