Fig. 4.
Allele frequency spectra of selected alleles under three malaria models. Under the host selection model, the spectra of alleles with s = 0·1 and 0·01 are more skewed toward high frequency alleles than the malaria neutral site-frequency spectrum, but less skewed than the WF neutral site-frequency spectrum. Under the transmission selection and host/transmission selection models, the spectra of alleles with s = 0·1 and 0·01 are more skewed toward high frequency alleles than both neutral frequency spectra, while the spectra of alleles with s = 0·001 are only more skewed than the malaria neutral frequency spectrum.